Research, Safety & Administration

Transparency is the foundation of biohacking. Explore safety profiles, research evidence tiers, and contraindications.

Safety & Contraindications

Peptides are powerful signaling molecules. Key risks to consider in research:

  • GHK-Cu / AHK-Cu: May cause zinc depletion over long-term use.
  • Insuliin / MOTS-c: Requires careful blood glucose monitoring due to hypoglycemia risks.
  • Semax / Selank: May temporarily increase hair shedding in susceptible individuals.

Administration Routes

Peptide bioavailability is entirely dependent on the route of administration:

  • Subkutaanne: Highest bioavailability. Standard for BPC-157, TB-500, Epithalon.
  • Intranasaalne: Best for crossing the blood-brain barrier (Semax, Selank, Insulin).
  • Suukaudne: Requires acid-stable molecules (Argino-BPC) or specific protective transporters (Pinealon).

Evidence Tiers

We transparently categorize all peptides into four tiers of evidence:

  • In-Vitro: Laboratory studies on isolated cells.
  • Loomkatsed: Studies conducted in rodent or mammalian models.
  • Kliinilised Uuringud: Formal human trials (often Russian/Eastern European clinical use, e.g., Cerebrolysin).
  • N=1 Eksperimendid: Anecdotal data from the global biohacking community.