Research, Safety & Administration
Transparency is the foundation of biohacking. Explore safety profiles, research evidence tiers, and contraindications.
Safety & Contraindications
Peptides are powerful signaling molecules. Key risks to consider in research:
- GHK-Cu / AHK-Cu: May cause zinc depletion over long-term use.
- Insuliin / MOTS-c: Requires careful blood glucose monitoring due to hypoglycemia risks.
- Semax / Selank: May temporarily increase hair shedding in susceptible individuals.
Administration Routes
Peptide bioavailability is entirely dependent on the route of administration:
- Subkutaanne: Highest bioavailability. Standard for BPC-157, TB-500, Epithalon.
- Intranasaalne: Best for crossing the blood-brain barrier (Semax, Selank, Insulin).
- Suukaudne: Requires acid-stable molecules (Argino-BPC) or specific protective transporters (Pinealon).
Evidence Tiers
We transparently categorize all peptides into four tiers of evidence:
- In-Vitro: Laboratory studies on isolated cells.
- Loomkatsed: Studies conducted in rodent or mammalian models.
- Kliinilised Uuringud: Formal human trials (often Russian/Eastern European clinical use, e.g., Cerebrolysin).
- N=1 Eksperimendid: Anecdotal data from the global biohacking community.